A Report of the Surgeon General: How Tobacco Smoke Causes Disease

The Biology and Behavioral Basis for Smoking-Attributable Disease

These files are available for downloading in PDF format. Persons using assistive technology may not be able to fully access information in these files. For assistance, contact tobaccoinfo@cdc.gov.

Title, Foreword, Preface, Acknowledgements, Table of Contents  (415KB)

Chapter 1: Introduction, Evaluation of Evidence on Mechanisms of Disease Production, and Summary  (801KB)

Chapter 2: The Changing Cigarette  (156KB)

Chapter 3: Chemistry and Toxicology of Cigarette Smoke and Biomarkers of Exposure and Harm  (681KB)

Chapter 4: Nicotine Addiction: Past and Present  (1.18MB)

Chapter 5: Cancer  (2.16MB)

Chapter 6: Cardiovascular Diseases  (991KB)

Chapter 7: Pulmonary Diseases  (4.11MB)

Chapter 8: Reproductive and Developmental Effects  (2.01MB)

Chapter 9: A Vision for the Future  (580KB)

Abbreviations, List of Tables and Figures, Definitions, Index  (277KB)

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